That's Mr. BoneHead to You!
What would you say if I told you that your bones can affect your liver, testes, fat stores, pancreas and your brain? Well, it does in mice thanks to a 49 amino acid protein called osteocalcin.
Gerard Karsenty has been studying osteocalcin for decades now and recently published a paper showing how bone plays a direct role in memory and mood. It seems that while being a protein, osteocalcin acts as a hormone and a "messenger, sent by bone to regulate crucial processes all over the body."
The question I'm left with: Is there a connection between osteocalcin and glia? Send your theories here. And do some resistance exercises.